RNA splicing of the BHC80 gene contributes to neuroendocrine prostate cancer progression

Prostate adenocarcinoma (AdPC) progression to treatment-induced neuroendocrine prostate cancer (t-NEPC) is associated with poor patient survival. While AdPC and t-NEPC share similar genomes, they possess distinct transcriptomes, suggesting that RNA splicing and epigenetic mechanisms may regulate t-NEPC development.

Patient-reported quality of life following stereotactic body radiotherapy and conventionally fractionated external beam radiotherapy compared with active surveillance among men with localized prostate cancer

Evidence supporting the efficacy of stereotactic body radiotherapy (SBRT) for localized prostate cancer is accumulating, but comparative studies of patient-reported quality of life (QOL) following SBRT versus conventionally fractionated external beam radiotherapy (EBRT) or active surveillance (AS) are limited.

Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study

Androgen receptor splice variant 7 (AR-V7) results in a truncated receptor, which leads to ligand-independent constitutive activation that is not inhibited by anti-androgen therapies, including abiraterone or enzalutamide.

Vidoes

ENZAMET trial by Prof. Sweeney and Prof. Davis

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EAU Guidelines on Prostate Cancer

This project was made possible by an educational grant of Janssen, the Pharmaceutical Companies of Johnson & Johnson

Articles

Patient-Centered Preference Assessment to Improve Satisfaction With Care Among Patients With Localized Prostate Cancer: A Randomized Controlled Trial

End-to-side Somatic-to-autonomic Nerve Grafting to Restore Erectile Function and Improve Quality of Life After Radical Prostatectomy

External Validation of the European Association of Urology Biochemical Recurrence Risk Groups to Predict Metastasis and Mortality After Radical Prostatectomy in a European Cohort

EAU Edu Platform on Prostate Cancer

RNA splicing of the BHC80 gene contributes to neuroendocrine prostate cancer progression

Patient-reported quality of life following stereotactic body radiotherapy and conventionally fractionated external beam radiotherapy compared with active surveillance among men with localized prostate cancer

Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study

Upcoming events

Asia-Pacific Prostate Cancer Conference 2019

Advanced Prostate Cancer Consensus Conference: APCCC 2019

16th Meeting of the EAU Robotic Urology Section (ERUS19)

Vidoes

ENZAMET trial by Prof. Sweeney and Prof. Davis

ARCHES trial by Prof. Stenzl

TITAN trial by Prof. Chi

MRI trial by Prof. Barentsz