Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, noninferiority, confirmatory study

An AI system was superior to radiologists using PI-RADS (2.1), on average, at detecting clinically significant prostate cancer and comparable to the standard of care. Such a system shows the potential to be a supportive tool within a primary diagnostic setting, with several associated benefits for patients and radiologists. Prospective validation is needed to test clinical applicability of this system.